MSL2 抗体 (AA 341-473)
Quick Overview for MSL2 抗体 (AA 341-473) (ABIN7151072)
抗原
See all MSL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 341-473
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human E3 ubiquitin-protein ligase MSL2 protein (341-473AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MSL2 (Male-Specific Lethal 2 Homolog (MSL2))
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别名
- MSL2
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背景
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Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at \\\'Lys-35\\\' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at \\\'Lys-4\\\' (H3K4me) and \\\'Lys-79\\\' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.
Aliases: Male specific lethal 2 homolog (Drosophila) antibody, Male specific lethal 2 homolog 1 antibody, Male specific lethal 2 homolog antibody, Male specific lethal 2 like 1 antibody, Male-specific lethal 2 homolog antibody, Male-specific lethal 2-like 1 antibody, Male-specific lethal-2 homolog 1 antibody, MSL-2 antibody, MSL2 antibody, MSL2-like 1 antibody, MSL2_HUMAN antibody, MSL2L1 antibody, Ring finger protein 184 antibody
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UniProt
- Q9HCI7
抗原
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