Deltex Homolog 1 抗体 (AA 261-410) (HRP)
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- 抗原 See all Deltex Homolog 1 (DTX1) 抗体
- Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
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抗原表位
- AA 261-410
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Deltex Homolog 1 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase DTX1 protein (261-410AA)
- 亚型
- IgG
- Top Product
- Discover our top product DTX1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
- 别名
- DTX1 (DTX1 产品)
- 别名
- hDx-1 antibody, Fxit1 antibody, mKIAA4160 antibody, deltex antibody, dtx antibody, xdtx1 antibody, deltex E3 ubiquitin ligase 1 antibody, deltex homolog 1 (Drosophila) antibody, deltex 1, E3 ubiquitin ligase antibody, deltex 1 L homeolog antibody, deltex 1 S homeolog antibody, DTX1 antibody, dtx1 antibody, Dtx1 antibody, dtx1.L antibody, dtx1.S antibody
- 背景
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Background: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.
Aliases: Deltex 1, E3 ubiquitin ligase antibody, Deltex antibody, Deltex homolog 1 (Drosophila) antibody, Deltex homolog 1 antibody, Deltex protein 1 antibody, Deltex-1 antibody, Deltex1 antibody, dtx1 antibody, DTX1_HUMAN antibody, E3 ubiquitin protein ligase DTX1 antibody, E3 ubiquitin-protein ligase DTX1 antibody, FXI-T1 antibody, Fxit 1 antibody, Fxit1 antibody, hDTX1 antibody, hDx 1 antibody, mDTX1 antibody, Protein deltex 1 antibody, Protein deltex-1 antibody
- UniProt
- Q86Y01
- 途径
- Notch Signaling
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