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Deltex Homolog 1 抗体 (AA 261-410) (FITC)

DTX1 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7151015
发货至: 中国
  • 抗原 See all Deltex Homolog 1 (DTX1) 抗体
    Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
    抗原表位
    • 16
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 261-410
    适用
    • 42
    • 25
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 42
    • 1
    克隆类型
    • 43
    多克隆
    标记
    • 15
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Deltex Homolog 1 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human E3 ubiquitin-protein ligase DTX1 protein (261-410AA)
    亚型
    IgG
    Top Product
    Discover our top product DTX1 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
    别名
    DTX1 (DTX1 产品)
    别名
    hDx-1 antibody, Fxit1 antibody, mKIAA4160 antibody, deltex antibody, dtx antibody, xdtx1 antibody, deltex E3 ubiquitin ligase 1 antibody, deltex homolog 1 (Drosophila) antibody, deltex 1, E3 ubiquitin ligase antibody, deltex 1 L homeolog antibody, deltex 1 S homeolog antibody, DTX1 antibody, dtx1 antibody, Dtx1 antibody, dtx1.L antibody, dtx1.S antibody
    背景

    Background: Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, suggesting that it can antagonize NOTCH1.

    Aliases: Deltex 1, E3 ubiquitin ligase antibody, Deltex antibody, Deltex homolog 1 (Drosophila) antibody, Deltex homolog 1 antibody, Deltex protein 1 antibody, Deltex-1 antibody, Deltex1 antibody, dtx1 antibody, DTX1_HUMAN antibody, E3 ubiquitin protein ligase DTX1 antibody, E3 ubiquitin-protein ligase DTX1 antibody, FXI-T1 antibody, Fxit 1 antibody, Fxit1 antibody, hDTX1 antibody, hDx 1 antibody, mDTX1 antibody, Protein deltex 1 antibody, Protein deltex-1 antibody

    UniProt
    Q86Y01
    途径
    Notch Signaling
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