ARIH2 抗体 (AA 43-360)
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- 抗原 See all ARIH2 抗体
- ARIH2 (protein ariadne-2 homolog (ARIH2))
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抗原表位
- AA 43-360
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARIH2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase ARIH2 protein (43-360AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ARIH2 (protein ariadne-2 homolog (ARIH2))
- 别名
- ARIH2 (ARIH2 产品)
- 别名
- ARI2 antibody, TRIAD1 antibody, AI843547 antibody, UIP48 antibody, wu:fa09c12 antibody, zgc:64093 antibody, ariadne RBR E3 ubiquitin protein ligase 2 antibody, ariadne RBR E3 ubiquitin protein ligase 2 L homeolog antibody, ariadne homolog 2 (Drosophila) antibody, ARIH2 antibody, Arih2 antibody, arih2.L antibody, arih2 antibody
- 背景
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Background: E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655). Mediates \\\'Lys-6\\\', \\\'Lys-48\\\'-and \\\'Lys-63\\\'-linked polyubiquitination (PubMed:16118314, PubMed:17646546, PubMed:19340006). May play a role in myelopoiesis (PubMed:19340006).
Aliases: HT005 antibody, all trans retinoic acid inducible RING finger antibody, Ari 2 antibody, Ari-2 antibody, ARI2 antibody, ARI2_HUMAN antibody, Ariadne 2 antibody, Ariadne 2 protein homolog antibody, ariadne homolog 2 (Drosophila) antibody, ariadne homolog 2 antibody, Ariadne RBR E3 ubiquitin protein ligase 2 antibody, ARIH 2 antibody, Arih2 antibody, E3 ubiquitin protein ligase ARIH2 antibody, E3 ubiquitin-protein ligase ARIH2 antibody, protein ariadne 2 homolog antibody, Protein ariadne-2 homolog antibody, Triad 1 antibody, TRIAD1 antibody, Triad1 protein antibody, UIP48 antibody
- UniProt
- O95376
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