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- 抗原 See all AMFR 抗体
- AMFR (Autocrine Motility Factor Receptor (AMFR))
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抗原表位
- AA 485-643
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AMFR antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 ubiquitin-protein ligase AMFR protein (485-643AA)
- 亚型
- IgG
- Top Product
- Discover our top product AMFR Primary Antibody
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anti-Autocrine Motility Factor Receptor (AMFR) (AA 456-643) antibody
AMFR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) (AA 571-601) antibodyAMFR 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) (AA 571-601) antibodyAMFR 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB4403-4404 unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) (AA 456-639) antibodyAMFR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) (C-Term) antibodyAMFR 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) antibodyAMFR 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) antibodyAMFR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) (AA 451-550) antibodyAMFR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) (AA 110-159) antibodyAMFR 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 兔, 豚鼠, 猴, Bat, 小鸡, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Autocrine Motility Factor Receptor (AMFR) (AA 371-400) antibodyAMFR 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- AMFR (Autocrine Motility Factor Receptor (AMFR))
- 别名
- AMFR (AMFR 产品)
- 别名
- GP78 antibody, RNF45 antibody, gp78 antibody, wu:fi06e06 antibody, wu:fi37e05 antibody, zgc:63893 antibody, rnf45 antibody, autocrine motility factor receptor antibody, autocrine motility factor receptor L homeolog antibody, autocrine motility factor receptor a antibody, autocrine motility factor receptor, amfr antibody, putative autocrine motility factor receptor, amfr antibody, AMFR antibody, Amfr antibody, amfr.L antibody, amfra antibody, amfr antibody, AaeL_AAEL005881 antibody, CpipJ_CPIJ016043 antibody, Smp_047420 antibody
- 背景
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Background: E3 ubiquitin-protein ligase that mediates the polyubiquitination of a number of proteins such as CD3D, CYP3A4, CFTR and APOB for proteasomal degradation. Component of a VCP/p97-AMFR/gp78 complex that participates in the final step of endoplasmic reticulum-associated degradation (ERAD). The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG complex at the ER membrane and initiating ubiquitination of HMGCR. The ubiquitinated HMGCR is then released from the ER by the complex into the cytosol for subsequent destruction. Also regulates ERAD through the ubiquitination of UBL4A a component of the BAG6/BAT3 complex. Also acts as a scaffold protein to assemble a complex that couples ubiquitination, retranslocation and deglycosylation. Mediates tumor invasion and metastasis as a receptor for the GPI/autocrine motility factor.
Aliases: AMF receptor antibody, AMF receptor isoform 1 antibody, AMF receptor isoform 2 antibody, AMFR antibody, AMFR2_HUMAN antibody, Autocrine motility factor receptor antibody, Autocrine motility factor receptor precursor, isoform 1 antibody, Autocrine motility factor receptor precursor, isoform 2 antibody, E3 ubiquitin-protein ligase AMFR antibody, gp78 antibody, isoform 2 antibody, RING finger protein 45 antibody, RNF 45 antibody, RNF45 antibody
- UniProt
- Q9UKV5
- 途径
- ER-Nucleus Signaling
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