PIAS4 抗体 (AA 66-241)
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- 抗原 See all PIAS4 抗体
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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抗原表位
- AA 66-241
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIAS4 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human E3 SUMO-protein ligase PIAS4 protein (66-241AA)
- 亚型
- IgG
- Top Product
- Discover our top product PIAS4 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:500-1:1000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
- 别名
- PIAS4 (PIAS4 产品)
- 别名
- PIASY antibody, Piasg antibody, ZMIZ6 antibody, pias4 antibody, piasy antibody, wu:fc54c11 antibody, wu:fi18c10 antibody, wu:fi20e09 antibody, wu:fk93f11 antibody, zgc:66410 antibody, piasg antibody, zmiz6 antibody, LOC100219439 antibody, Pias-gamma antibody, pias4l antibody, wu:fi26h11 antibody, zgc:63923 antibody, protein inhibitor of activated STAT 4 antibody, protein inhibitor of activated STAT, 4 antibody, protein inhibitor of activated STAT, 4a antibody, protein inhibitor of activated STAT 4 L homeolog antibody, protein inhibitor of activated STAT, 4b antibody, PIAS4 antibody, Pias4 antibody, pias4a antibody, pias4.L antibody, pias4 antibody, pias4b antibody
- 背景
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Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
Aliases: E3 SUMO protein ligase PIAS4 antibody, E3 SUMO-protein ligase PIAS4 antibody, FLJ12419 antibody, MGC35296 antibody, PAIASgamma antibody, PIAS 4 antibody, PIAS gamma antibody, PIAS-gamma antibody, Pias4 antibody, PIAS4_HUMAN antibody, PIASG antibody, PIASgamma antibody, PIASy antibody, Protein inhibitor of activated STAT 4 antibody, Protein inhibitor of activated STAT protein 4 antibody, Protein inhibitor of activated STAT protein gamma antibody, Protein inhibitor of activated STAT protein PIASy antibody, Zinc finger MIZ type containing 6 antibody, ZMIZ 6 antibody, ZMIZ6 antibody
- UniProt
- Q8N2W9
- 途径
- JAK/STAT Signaling, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
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