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PIAS3 抗体 (AA 399-628)

PIAS3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7150969
发货至: 中国
  • 抗原 See all PIAS3 抗体
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    抗原表位
    • 6
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    AA 399-628
    适用
    • 34
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    • 16
    • 6
    • 5
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    • 3
    • 3
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    • 1
    宿主
    • 31
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    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 27
    • 1
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    This PIAS3 antibody is un-conjugated
    应用范围
    • 25
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    Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628AA)
    亚型
    IgG
    Top Product
    Discover our top product PIAS3 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
    别名
    PIAS3 (PIAS3 产品)
    别名
    PIAS3 antibody, Pias3l antibody, ZMIZ5 antibody, protein inhibitor of activated STAT 3 antibody, protein inhibitor of activated STAT, 3 antibody, protein inhibitor of activated STAT 3 L homeolog antibody, PIAS3 antibody, pias3 antibody, Pias3 antibody, pias3.L antibody
    背景

    Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.

    Aliases: E3 SUMO protein ligase PIAS 3 antibody, E3 SUMO protein ligase PIAS3 antibody, E3 SUMO-protein ligase PIAS3 antibody, FLJ14651 antibody, OTTHUMP00000015586 antibody, OTTHUMP00000015587 antibody, PIAS 3 antibody, Pias3 antibody, PIAS3 protein antibody, PIAS3_HUMAN antibody, Protein inhibitor of activated STAT 3 antibody, Protein inhibitor of activated STAT protein 3 antibody, Protein inhibitor of activated STAT3 antibody, Zinc finger MIZ type containing 5 antibody, ZMIZ 5 antibody, ZMIZ5 antibody

    UniProt
    Q9Y6X2
    途径
    JAK/STAT Signaling
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