CBX4 抗体 (AA 401-560)
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- 抗原 See all CBX4 抗体
- CBX4 (Chromobox Homolog 4 (CBX4))
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抗原表位
- AA 401-560
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBX4 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity purified
- 免疫原
- Recombinant Human E3 SUMO-protein ligase CBX4 protein (401-560AA)
- 亚型
- IgG
- Top Product
- Discover our top product CBX4 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CBX4 (Chromobox Homolog 4 (CBX4))
- 别名
- CBX4 (CBX4 产品)
- 别名
- MPc2 antibody, PC2 antibody, NBP16 antibody, XPolycomb antibody, cbx4-a antibody, im:6911625 antibody, zgc:158588 antibody, chromobox 4 antibody, chromobox 4 S homeolog antibody, chromobox homolog 4 antibody, chromobox homolog 4 (Pc class homolog, Drosophila) antibody, CBX4 antibody, Cbx4 antibody, cbx4.S antibody, cbx4 antibody
- 背景
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Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility.
Aliases: CBX 4 antibody, CBX4 antibody, Cbx4 chromobox homolog 4 (Drosophila Pc class) antibody, CBX4_HUMAN antibody, Chromobox homolog 4 (Pc class homolog, Drosophila) antibody, Chromobox homolog 4 antibody, Chromobox protein homolog 4 antibody, E3 SUMO protein ligase CBX 4 antibody, E3 SUMO protein ligase CBX4 antibody, E3 SUMO-protein ligase CBX4 antibody, hPc 2 antibody, hPc2 antibody, NBP 16 antibody, NBP16 antibody, NS5ATP1 binding protein 16 antibody, Pc 2 antibody, Pc class 2 homolog antibody, Pc class homolog antibody, Pc class homolog Drosophila antibody, PC2 antibody, Polycomb 2 homolog antibody
- UniProt
- O00257
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