DAD1 抗体 (AA 1-113)
Quick Overview for DAD1 抗体 (AA 1-113) (ABIN7150599)
抗原
See all DAD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-113
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein (1-113AA)
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亚型
- IgG
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anti-Defender Against Cell Death 1 (DAD1) (AA 1-113) antibody
DAD1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2B4-C8 unconjugated
anti-Defender Against Cell Death 1 (DAD1) (AA 1-100) antibodyDAD1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Defender Against Cell Death 1 (DAD1) antibodyDAD1 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DAD1 (Defender Against Cell Death 1 (DAD1))
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别名
- DAD1
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背景
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Background: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:22467853). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes. Loss of the DAD1 protein triggers apoptosis (PubMed:22467853).
Aliases: DAD 1 antibody, DAD-1 antibody, dad1 antibody, DAD1_HUMAN antibody, Defender against cell death 1 antibody, Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, Oligosaccharyl transferase subunit DAD1 antibody, OST 2 antibody, OST2 antibody
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UniProt
- P61803
抗原
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