DNAJC1 抗体 (AA 521-793) (HRP)
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- 抗原 See all DNAJC1 抗体
- DNAJC1 (DnaJ (Hsp40) Homolog, Subfamily C, Member 1 (DNAJC1))
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抗原表位
- AA 521-793
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DNAJC1 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human DnaJ homolog subfamily C member 10 protein (521-793AA)
- 亚型
- IgG
- Top Product
- Discover our top product DNAJC1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DNAJC1 (DnaJ (Hsp40) Homolog, Subfamily C, Member 1 (DNAJC1))
- 别名
- DNAJC1 (DNAJC1 产品)
- 别名
- dnajc1l antibody, zgc:152779 antibody, DNAJL1 antibody, ERdj1 antibody, HTJ1 antibody, MTJ1 antibody, 4733401K02Rik antibody, AA960110 antibody, D230036H06Rik antibody, Dnajl1 antibody, ERj1p antibody, DnaJ heat shock protein family (Hsp40) member C1 antibody, DnaJ (Hsp40) homolog, subfamily C, member 1 antibody, DnaJ heat shock protein family (Hsp40) member C1 S homeolog antibody, dnajc1 antibody, DNAJC1 antibody, Dnajc1 antibody, dnajc1.S antibody
- 背景
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Background: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress.
Aliases: DNAJC10 antibody, ERDJ5 antibody, UNQ495/PRO1012DnaJ homolog subfamily C member 10 antibody, EC 1.8.4.- antibody, Endoplasmic reticulum DNA J domain-containing protein 5 antibody, ER-resident protein ERdj5 antibody, ERdj5 antibody, Macrothioredoxin antibody, MTHr antibody
- UniProt
- Q8IXB1
- 途径
- Chromatin Binding
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