POLR3E 抗体 (AA 1-260)
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- 抗原 See all POLR3E 抗体
- POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
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抗原表位
- AA 1-260
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR3E antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
- 亚型
- IgG
- Top Product
- Discover our top product POLR3E Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
- 别名
- POLR3E (POLR3E 产品)
- 别名
- RPC5 antibody, SIN antibody, Sin antibody, MGC78924 antibody, RGD1308086 antibody, wu:fb12d10 antibody, wu:fs42e03 antibody, zgc:55592 antibody, RNA polymerase III subunit E antibody, polymerase (RNA) III (DNA directed) polypeptide E antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, POLR3E antibody, Polr3e antibody, polr3e.L antibody, polr3e antibody, LOC608689 antibody
- 背景
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Aliases: POLR3E antibody, KIAA1452 antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, RNA polymerase III subunit C5 antibody, DNA-directed RNA polymerase III 80 kDa polypeptide antibody
- UniProt
- Q9NVU0
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