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POLR3E 抗体 (AA 1-260)

POLR3E 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7150462
发货至: 中国
  • 抗原 See all POLR3E 抗体
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    抗原表位
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-260
    适用
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 21
    • 2
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR3E antibody is un-conjugated
    应用范围
    • 9
    • 9
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human DNA-directed RNA polymerase III subunit RPC5 protein (1-260AA)
    亚型
    IgG
    Top Product
    Discover our top product POLR3E Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    POLR3E (Polymerase (RNA) III (DNA Directed) Polypeptide E (80kD) (POLR3E))
    别名
    POLR3E (POLR3E 产品)
    别名
    RPC5 antibody, SIN antibody, Sin antibody, MGC78924 antibody, RGD1308086 antibody, wu:fb12d10 antibody, wu:fs42e03 antibody, zgc:55592 antibody, RNA polymerase III subunit E antibody, polymerase (RNA) III (DNA directed) polypeptide E antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide E (80kD) antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, POLR3E antibody, Polr3e antibody, polr3e.L antibody, polr3e antibody, LOC608689 antibody
    背景

    Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).

    Aliases: POLR3E antibody, KIAA1452 antibody, DNA-directed RNA polymerase III subunit RPC5 antibody, RNA polymerase III subunit C5 antibody, DNA-directed RNA polymerase III 80 kDa polypeptide antibody

    UniProt
    Q9NVU0
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