POLR2D 抗体 (AA 1-142) (HRP)
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- 抗原 See all POLR2D 抗体
- POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
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抗原表位
- AA 1-142
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR2D antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human DNA-directed RNA polymerase II subunit RPB4 protein (1-142AA)
- 亚型
- IgG
- Top Product
- Discover our top product POLR2D Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
- 别名
- POLR2D (POLR2D 产品)
- 别名
- wu:fa95b11 antibody, zgc:110435 antibody, HSRBP4 antibody, HSRPB4 antibody, RBP4 antibody, RPB16 antibody, 2310002G05Rik antibody, 2610028L19Rik antibody, RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, polymerase (RNA) II (DNA directed) polypeptide D antibody, Polr2d antibody, CpipJ_CPIJ006734 antibody, UREG_01395 antibody, LOC100282338 antibody, polr2d antibody, POLR2D antibody
- 背景
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Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.
Aliases: DNA directed RNA polymerase II 16 kDa polypeptide antibody, DNA directed RNA polymerase II subunit D antibody, DNA directed RNA polymerase II subunit RPB4 antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, DNA-directed RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II subunit rpb4 antibody, HSRBP4 antibody, HSRPB4 antibody, polr2d antibody, polymerase RNA II DNA directed polypeptide D antibody, RBP4 antibody, RNA polymerase II 16 kDa subunit antibody, RNA polymerase II subunit B4 antibody, RNA polymerase II subunit D antibody, RNA polymerase II subunit hsRBP4 antibody, RPB16 antibody, RPB4_HUMAN antibody
- UniProt
- O15514
- 途径
- Regulatory RNA Pathways
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