电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

RFX6 抗体 (AA 1-260) (Biotin)

RFX6 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7150386
发货至: 中国
  • 抗原 See all RFX6 抗体
    RFX6 (Regulatory Factor X 6 (RFX6))
    抗原表位
    • 4
    • 4
    • 1
    • 1
    • 1
    AA 1-260
    适用
    • 19
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 17
    • 2
    克隆类型
    • 19
    多克隆
    标记
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RFX6 antibody is conjugated to Biotin
    应用范围
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human DNA-binding protein RFX6 protein (1-260AA)
    亚型
    IgG
    Top Product
    Discover our top product RFX6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RFX6 (Regulatory Factor X 6 (RFX6))
    别名
    RFX6 (RFX6 产品)
    别名
    MTFS antibody, RFXDC1 antibody, dJ955L16.1 antibody, 4930572O07Rik antibody, Rfxdc1 antibody, regulatory factor X6 antibody, regulatory factor X, 6 antibody, RFX6 antibody, Rfx6 antibody
    背景

    Background: Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin (PubMed:20148032, PubMed:25497100). Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes (PubMed:20148032). Involved in glucose-stimulated insulin secretion by promoting insulin and L-type calcium channel gene transcription (PubMed:25497100).

    Aliases: RFX6 antibody, RFXDC1 antibody, DNA-binding protein RFX6 antibody, Regulatory factor X 6 antibody, Regulatory factor X domain-containing protein 1 antibody

    UniProt
    Q8HWS3
    途径
    Carbohydrate Homeostasis
You are here:
客服