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- 抗原 See all RFX6 抗体
- RFX6 (Regulatory Factor X 6 (RFX6))
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抗原表位
- AA 1-260
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFX6 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human DNA-binding protein RFX6 protein (1-260AA)
- 亚型
- IgG
- Top Product
- Discover our top product RFX6 Primary Antibody
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anti-Regulatory Factor X 6 (RFX6) (AA 1-928) antibody
RFX6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 6 (RFX6) antibodyRFX6 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulatory Factor X 6 (RFX6) (AA 1-928) antibodyRFX6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulatory Factor X 6 (RFX6) (Middle Region) antibodyRFX6 适用: 人, 小鼠, 豚鼠, 马, 兔, Cow, 大鼠, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- RFX6 (Regulatory Factor X 6 (RFX6))
- 别名
- RFX6 (RFX6 产品)
- 别名
- MTFS antibody, RFXDC1 antibody, dJ955L16.1 antibody, 4930572O07Rik antibody, Rfxdc1 antibody, regulatory factor X6 antibody, regulatory factor X, 6 antibody, RFX6 antibody, Rfx6 antibody
- 背景
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Background: Transcription factor required to direct islet cell differentiation during endocrine pancreas development. Specifically required for the differentiation of 4 of the 5 islet cell types and for the production of insulin (PubMed:20148032, PubMed:25497100). Not required for pancreatic PP (polypeptide-producing) cells differentiation. Acts downstream of NEUROG3 and regulates the transcription factors involved in beta-cell maturation and function, thereby restricting the expression of the beta-cell differentiation and specification genes, and thus the beta-cell fate choice. Activates transcription by forming a heterodimer with RFX3 and binding to the X-box in the promoter of target genes (PubMed:20148032). Involved in glucose-stimulated insulin secretion by promoting insulin and L-type calcium channel gene transcription (PubMed:25497100).
Aliases: RFX6 antibody, RFXDC1 antibody, DNA-binding protein RFX6 antibody, Regulatory factor X 6 antibody, Regulatory factor X domain-containing protein 1 antibody
- UniProt
- Q8HWS3
- 途径
- Carbohydrate Homeostasis
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