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POLH 抗体 (AA 408-609)

POLH 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7150247
发货至: 中国
  • 抗原 See all POLH 抗体
    POLH (Polymerase (DNA Directed), eta (POLH))
    抗原表位
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 408-609
    适用
    • 42
    • 12
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 3
    克隆类型
    • 44
    • 1
    多克隆
    标记
    • 18
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLH antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 11
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human DNA polymerase eta protein (408-609AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    POLH (Polymerase (DNA Directed), eta (POLH))
    别名
    POLH (POLH 产品)
    背景

    Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5\\\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

    Aliases: DNA polymerase eta antibody, FLJ16395 antibody, FLJ21978 antibody, Polh antibody, POLH_HUMAN antibody, polymerase DNA directed eta antibody, RAD30 antibody, RAD30 homolog A antibody, RAD30A antibody, Xeroderma pigmentosum variant type protein antibody, XP V antibody, XPV antibody

    UniProt
    Q9Y253
    途径
    DNA Damage Repair
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