APOBEC3C 抗体 (AA 1-190)
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- 抗原 See all APOBEC3C 抗体
- APOBEC3C (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C))
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抗原表位
- AA 1-190
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APOBEC3C antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human DNA dC->dU-editing enzyme APOBEC-3C protein (1-190AA)
- 亚型
- IgG
- Top Product
- Discover our top product APOBEC3C Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- APOBEC3C (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3C (APOBEC3C))
- 别名
- APOBEC3C (APOBEC3C 产品)
- 别名
- APOBEC3C antibody, A3C antibody, APOBEC1L antibody, ARDC2 antibody, ARDC4 antibody, ARP5 antibody, PBI antibody, bK150C2.3 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3C antibody, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C antibody, APOBEC3C antibody
- 背景
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Background: DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV), herpes simplex virus 1 (HHV-1) and Epstein-Barr virus (EBV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
Aliases: A3C antibody, ABC3C_HUMAN antibody, APOBEC1 like antibody, APOBEC1-like antibody, APOBEC1L antibody, APOBEC3C antibody, Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C antibody, ARDC2 antibody, ARDC4 antibody, ARP5 antibody, bK150C2.3 antibody, DNA dC >dU editing enzyme APOBEC 3C antibody, MGC19485 antibody, PBI antibody, Phorbolin I antibody, Phorbolin I protein antibody, Probable DNA dC dU editing enzyme APOBEC 3C antibody, Probable DNA dC->dU-editing enzyme APOBEC-3C antibody
- UniProt
- Q9NRW3
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