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- 抗原 See all ZRANB3 products
- ZRANB3 (Zinc Finger, RAN-Binding Domain Containing 3 (ZRANB3))
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抗原表位
- AA 370-624
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZRANB3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human DNA annealing helicase and endonuclease ZRANB3 protein (370-624AA)
- 亚型
- IgG
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anti-Zinc Finger, RAN-Binding Domain Containing 3 (ZRANB3) (AA 818-1077) antibody
ZRANB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, RAN-Binding Domain Containing 3 (ZRANB3) antibodyZRANB3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ZRANB3 (Zinc Finger, RAN-Binding Domain Containing 3 (ZRANB3))
- 别名
- ZRANB3 (ZRANB3 产品)
- 别名
- 4933425L19Rik antibody, AH2 antibody, AI316834 antibody, C730006D09 antibody, zinc finger RANBP2-type containing 3 antibody, zinc finger, RAN-binding domain containing 3 antibody, ZRANB3 antibody, Zranb3 antibody
- 背景
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Background: DNA annealing helicase and endonuclease required to maintain genome stability at stalled or collapsed replication forks by facilitating fork restart and limiting inappropriate recombination that could occur during template switching events. Recruited to the sites of stalled DNA replication by polyubiquitinated PCNA and acts as a structure-specific endonuclease that cleaves the replication fork D-loop intermediate, generating an accessible 3\\\'-OH group in the template of the leading strand, which is amenable to extension by DNA polymerase. In addition to endonuclease activity, also catalyzes the fork regression via annealing helicase activity in order to prevent disintegration of the replication fork and the formation of double-strand breaks.
Aliases: 4933425L19Rik antibody, AH2 antibody, Annealing helicase 2 antibody, DNA annealing helicase and endonuclease ZRANB3 antibody, MGC105033 antibody, MGC75012 antibody, OTTHUMP00000197449 antibody, Zinc finger Ran-binding domain-containing protein 3 antibody, Zinc finger, RAN- binding domain containing 3 antibody, ZRAB3_HUMAN antibody, Zranb3 antibody
- UniProt
- Q5FWF4
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