DISC1 抗体 (AA 99-325)
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- 抗原 See all DISC1 抗体
- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
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抗原表位
- AA 99-325
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DISC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Disrupted in schizophrenia 1 protein (99-325AA)
- 亚型
- IgG
- Top Product
- Discover our top product DISC1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
- 别名
- DISC1 (DISC1 产品)
- 别名
- DISC1 antibody, C1orf136 antibody, SCZD9 antibody, disrupted in schizophrenia 1 antibody, disrupted in schizophrenia 1 protein antibody, disc1 antibody, DISC1 antibody, LOC100580606 antibody, Disc1 antibody
- 背景
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Background: Involved in the regulation of multiple aspects of embryonic and adult neurogenesis. Required for neural progenitor proliferation in the ventrical/subventrical zone during embryonic brain development and in the adult dentate gyrus of the hippocampus. Participates in the Wnt-mediated neural progenitor proliferation as a positive regulator by modulating GSK3B activity and CTNNB1 abundance. Plays a role as a modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including neuron positioning, dendritic development and synapse formation. Inhibits the activation of AKT-mTOR signaling upon interaction with CCDC88A. Regulates the migration of early-born granule cell precursors toward the dentate gyrus during the hippocampal development. Plays a role, together with PCNT, in the microtubule network formation.
Aliases: C1orf136 antibody, DISC1 antibody, DISC1_HUMAN antibody, Disrupted in schizophrenia 1 antibody, Disrupted in schizophrenia 1 protein antibody, KIAA0457 antibody, RP4-730B13.1 antibody, SCZD9 antibody
- UniProt
- Q9NRI5
- 途径
- Regulation of Cell Size
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