SAMHD1 抗体 (AA 1-314)
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- 抗原 See all SAMHD1 抗体
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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抗原表位
- AA 1-314
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SAMHD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Antigen Affinity purified & Affinity purified
- 免疫原
- Recombinant Human Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 protein (1-314AA)
- 亚型
- IgG
- Top Product
- Discover our top product SAMHD1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:100-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
- 别名
- SAMHD1 (SAMHD1 产品)
- 别名
- CHBL2 antibody, DCIP antibody, HDDC1 antibody, MOP-5 antibody, SBBI88 antibody, si:dkeyp-44b8.8 antibody, E330031J07Rik antibody, Mg11 antibody, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain, 1 antibody, SAMHD1 antibody, samhd1 antibody, Samhd1 antibody
- 背景
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Background: Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling (PubMed:18546154, PubMed:19525956, PubMed:22056990, PubMed:24336198, PubMed:28229507). Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction (PubMed:25038827).
Aliases: CHBL2 antibody, DCIP antibody, Dendritic cell derived IFNG induced protein antibody, Dendritic cell-derived IFNG-induced protein antibody, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 antibody, dNTPase antibody, HD domain containing 1 antibody, HDDC1 antibody, Mg11 antibody, Monocyte protein 5 antibody, MOP 5 antibody, MOP-5 antibody, MOP5 antibody, OTTHUMP00000030889 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain containing protein 1 antibody, SAM domain and HD domain-containing protein 1 antibody, SAMH1_HUMAN antibody, Samhd1 antibody, SBBI88 antibody
- UniProt
- Q9Y3Z3
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