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DOCK3 抗体 (AA 1630-1934) (Biotin)

DOCK3 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7149588
发货至: 中国
  • 抗原 See all DOCK3 抗体
    DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))
    抗原表位
    • 4
    • 1
    • 1
    AA 1630-1934
    适用
    • 7
    • 1
    宿主
    • 6
    • 1
    克隆类型
    • 7
    多克隆
    标记
    • 4
    • 2
    • 1
    This DOCK3 antibody is conjugated to Biotin
    应用范围
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)
    亚型
    IgG
    Top Product
    Discover our top product DOCK3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))
    别名
    DOCK3 (DOCK3 产品)
    别名
    MOCA antibody, PBP antibody, mKIAA0299 antibody, dedicator of cytokinesis 3 antibody, similar to dedicator of cytokinesis 3 antibody, dedicator of cytokinesis protein 3 antibody, dedicator of cyto-kinesis 3 antibody, DOCK3 antibody, LOC561387 antibody, dock3 antibody, LOC100474164 antibody, Dock3 antibody
    背景

    Background: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).

    Aliases: DOCK3 antibody, KIAA0299 antibody, MOCADedicator of cytokinesis protein 3 antibody, Modifier of cell adhesion antibody, Presenilin-binding protein antibody, PBP antibody

    UniProt
    Q8IZD9
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