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- 抗原 See all DOCK3 抗体
- DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))
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抗原表位
- AA 1630-1934
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOCK3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))
- 别名
- DOCK3 (DOCK3 产品)
- 别名
- MOCA antibody, PBP antibody, mKIAA0299 antibody, dedicator of cytokinesis 3 antibody, similar to dedicator of cytokinesis 3 antibody, dedicator of cytokinesis protein 3 antibody, dedicator of cyto-kinesis 3 antibody, DOCK3 antibody, LOC561387 antibody, dock3 antibody, LOC100474164 antibody, Dock3 antibody
- 背景
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Background: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).
Aliases: DOCK3 antibody, KIAA0299 antibody, MOCADedicator of cytokinesis protein 3 antibody, Modifier of cell adhesion antibody, Presenilin-binding protein antibody, PBP antibody
- UniProt
- Q8IZD9
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