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DAPK3 抗体 (AA 283-401)

DAPK3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7149558
发货至: 中国
  • 抗原 See all DAPK3 抗体
    DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
    抗原表位
    • 17
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
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    • 3
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    • 2
    • 2
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    • 1
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    AA 283-401
    适用
    • 54
    • 49
    • 27
    • 2
    • 1
    • 1
    • 1
    宿主
    • 80
    • 3
    克隆类型
    • 81
    • 2
    多克隆
    标记
    • 35
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DAPK3 antibody is un-conjugated
    应用范围
    • 69
    • 35
    • 26
    • 26
    • 25
    • 9
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Death-associated protein kinase 3 protein (283-401AA)
    亚型
    IgG
    Top Product
    Discover our top product DAPK3 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    DAPK3 (Death-Associated Protein Kinase 3 (DAPK3))
    别名
    DAPK3 (DAPK3 产品)
    别名
    DAPK3 antibody, dapk3 antibody, wu:fc25b08 antibody, si:dkey-57k2.5 antibody, MGC114871 antibody, ZIP antibody, ZIPK antibody, dlk antibody, Dapkl antibody, death associated protein kinase 3 antibody, death-associated protein kinase 3 antibody, death-associated protein kinase 3 L homeolog antibody, DAPK3 antibody, dapk3 antibody, dapk3.L antibody, Dapk3 antibody
    背景

    Background: Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting. Involved in regulation of starvation-induced autophagy. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A, the inhibition of SMPP1M functions to enhance muscle responsiveness to Ca(2+) and promote a contractile state. Phosphorylates MYL12B in non-muscle cells leading to reorganization of actin cytoskeleton. Isoform 2 can phosphorylate myosin, PPP1R12A and MYL12B. Overexpression leads to condensation of actin stress fibers into thick bundles. Involved in actin filament focal adhesion dynamics. The function in both reorganization of actin cytoskeleton and focal adhesion dissolution is modulated by RhoD. Positively regulates canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2. Phosphorylates RPL13A on \\\'Ser-77\\\' upon interferon-gamma activation which is causing RPL13A release from the ribosome, RPL13A association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition. Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Involved in regulation of cell cycle progression and cell proliferation. May be a tumor suppressor.

    Aliases: DAP kinase 3 antibody, DAP like kinase antibody, DAP-like kinase antibody, Dapk 3 antibody, DAPK3 antibody, DAPK3_HUMAN antibody, Death associated kinase 3 antibody, Death associated protein kinase 3 antibody, Death-associated protein kinase 3 antibody, Dlk antibody, EC 2.7.11.1 antibody, FLJ36473 antibody, MYPT1 kinase antibody, ZIP antibody, ZIP kinase antibody, ZIP kinase isoform antibody, ZIP-kinase antibody, ZIPK antibody, zipper-interacting protein kinase antibody

    UniProt
    O43293
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