CPEB4 抗体 (AA 244-515) (HRP)
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- 抗原 See all CPEB4 products
- CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))
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抗原表位
- AA 244-515
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CPEB4 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Cytoplasmic polyadenylation element-binding protein 4 protein (244-515AA)
- 亚型
- IgG
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anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (N-Term) antibody
CPEB4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (AA 244-515) antibodyCPEB4 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (AA 109-137), (N-Term) antibodyCPEB4 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27196 unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (AA 72-121) antibodyCPEB4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4) (N-Term) antibodyCPEB4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))
- 别名
- CPEB4 (CPEB4 产品)
- 别名
- DKFZp468L052 antibody, 4930447D24Rik antibody, AI851572 antibody, mKIAA1673 antibody, Cpeb3 antibody, zgc:66166 antibody, cytoplasmic polyadenylation element binding protein 4 antibody, cytoplasmic polyadenylation element binding protein 4 S homeolog antibody, cytoplasmic polyadenylation element binding protein 4a antibody, CPEB4 antibody, cpeb4 antibody, cpeb4.S antibody, Cpeb4 antibody, cpeb4a antibody
- 背景
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Background: Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\\\'-UUUUUAU-3\\\') within the mRNA 3\\\'-UTR (PubMed:24990967). RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967). Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited (By similarity). Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195). Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752). Stimulates proliferation of melanocytes (PubMed:27857118). In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory (By similarity).
Aliases: CPE binding protein 4 antibody, CPE-binding protein 4 antibody, CPE-BP4 antibody, cpeb4 antibody, CPEB4_HUMAN antibody, Cytoplasmic polyadenylation element binding protein 4 antibody, Cytoplasmic polyadenylation element-binding protein 4 antibody, hCPEB-4 antibody, KIAA1673 antibody
- UniProt
- Q17RY0
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