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CPEB4 抗体 (AA 244-515) (FITC)

CPEB4 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7149350
发货至: 中国
  • 抗原 See all CPEB4 products
    CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))
    抗原表位
    • 9
    • 8
    • 6
    • 4
    • 1
    • 1
    AA 244-515
    适用
    • 29
    • 13
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 29
    克隆类型
    • 29
    多克隆
    标记
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPEB4 antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Cytoplasmic polyadenylation element-binding protein 4 protein (244-515AA)
    亚型
    IgG
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CPEB4 (Cytoplasmic Polyadenylation Element Binding Protein 4 (CPEB4))
    别名
    CPEB4 (CPEB4 产品)
    别名
    DKFZp468L052 antibody, 4930447D24Rik antibody, AI851572 antibody, mKIAA1673 antibody, Cpeb3 antibody, zgc:66166 antibody, cytoplasmic polyadenylation element binding protein 4 antibody, cytoplasmic polyadenylation element binding protein 4 S homeolog antibody, cytoplasmic polyadenylation element binding protein 4a antibody, CPEB4 antibody, cpeb4 antibody, cpeb4.S antibody, Cpeb4 antibody, cpeb4a antibody
    背景

    Background: Sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element (CPE), an uridine-rich sequence element (consensus sequence 5\\\'-UUUUUAU-3\\\') within the mRNA 3\\\'-UTR (PubMed:24990967). RNA binding results in a clear conformational change analogous to the Venus fly trap mechanism (PubMed:24990967). Regulates activation of unfolded protein response (UPR) in the process of adaptation to ER stress in liver, by maintaining translation of CPE-regulated mRNAs in conditions in which global protein synthesis is inhibited (By similarity). Required for cell cycle progression, specifically for cytokinesis and chromosomal segregation (PubMed:26398195). Plays a role as an oncogene promoting tumor growth and progression by positively regulating translation of t-plasminogen activator/PLAT (PubMed:22138752). Stimulates proliferation of melanocytes (PubMed:27857118). In contrast to CPEB1 and CPEB3, does not play role in synaptic plasticity, learning and memory (By similarity).

    Aliases: CPE binding protein 4 antibody, CPE-binding protein 4 antibody, CPE-BP4 antibody, cpeb4 antibody, CPEB4_HUMAN antibody, Cytoplasmic polyadenylation element binding protein 4 antibody, Cytoplasmic polyadenylation element-binding protein 4 antibody, hCPEB-4 antibody, KIAA1673 antibody

    UniProt
    Q17RY0
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