CST3 抗体
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- 抗原 See all CST3 抗体
- CST3 (Cystatin C (CST3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CST3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Protein G purified
- 免疫原
- Recombinant Human Cystatin C protein
- 克隆位点
- 3A1B7
- 亚型
- IgG2b
- Top Product
- Discover our top product CST3 Primary Antibody
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- 应用备注
- Recommended dilution:IHC:1:50-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CST3 (Cystatin C (CST3))
- 别名
- CST3 (CST3 产品)
- 别名
- armd11 antibody, fb51d07 antibody, wu:fb24g06 antibody, wu:fb51d07 antibody, wu:fc55f03 antibody, zgc:136227 antibody, ARMD11 antibody, CysC antibody, CYSC antibody, cystatin C antibody, cystatin C L homeolog antibody, cystatin C (amyloid angiopathy and cerebral hemorrhage) antibody, cystatin 3 antibody, CST3 antibody, cst3.L antibody, cst3 antibody, cystatin 3 antibody, Cst3 antibody
- 背景
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Background: Defects in CST3 are the cause of amyloidosis type 6 (AMYL6) [MIM:105150], also known as hereditary cerebral hemorrhage with amyloidosis (HCHWA), cerebral amyloid angiopathy (CAA) or cerebroarterial amyloidosis Icelandic type. AMYL6 is a hereditary generalized amyloidosis due to cystatin C amyloid deposition. Cystatin C amyloid accumulates in the walls of arteries, arterioles, and sometimes capillaries and veins of the brain, and in various organs including lymphoid tissue, spleen, salivary glands, and seminal vesicles. Amyloid deposition in the cerebral vessels results in cerebral amyloid angiopathy, cerebral hemorrhage and premature stroke. Cystatin C levels in the cerebrospinal fluid are abnormally low.Genetic variations in CST3 are associated with age-related macular degeneration type 11 (ARMD11) [MIM:611953]. ARMD is a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane.
Aliases: CysC,Cystatin-3,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin
- UniProt
- P01034
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