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CDK12 抗体 (AA 1309-1490) (HRP)

CRKRS 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7148854
发货至: 中国
  • 抗原 See all CDK12 (CRKRS) 抗体
    CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
    抗原表位
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1309-1490
    适用
    • 31
    • 11
    • 4
    • 1
    • 1
    • 1
    • 1
    宿主
    • 28
    • 3
    克隆类型
    • 28
    • 3
    多克隆
    标记
    • 17
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK12 antibody is conjugated to HRP
    应用范围
    • 18
    • 16
    • 4
    • 2
    • 2
    • 2
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Cyclin-dependent kinase 12 protein (1309-1490AA)
    亚型
    IgG
    Top Product
    Discover our top product CRKRS Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CDK12 (CRKRS) (Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS))
    别名
    CDK12 (CRKRS 产品)
    别名
    AC017581 antibody, CG7597 antibody, Dmel\\CG7597 antibody, anon-WO0140519.165 antibody, cg7597 antibody, dCDK12 antibody, gi24668141 antibody, CRK7 antibody, CRKR antibody, CRKRS antibody, hCDK12 antibody, 1810022J16Rik antibody, AI646528 antibody, Crk7 antibody, Crkrs antibody, D11Ertd752e antibody, Pksc antibody, Cyclin-dependent kinase 12 antibody, cyclin dependent kinase 12 antibody, cyclin-dependent kinase 12 antibody, Cdk12 antibody, CDK12 antibody
    背景

    Background: Cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A), thereby acting as a key regulator of transcription elongation. Regulates the expression of genes involved in DNA repair and is required for the maintenance of genomic stability. Preferentially phosphorylates \'Ser-5\' in CTD repeats that are already phosphorylated at \'Ser-7\', but can also phosphorylate \'Ser-2\'. Required for RNA splicing, possibly by phosphorylating SRSF1/SF2. Involved in regulation of MAP kinase activity, possibly leading to affect the response to estrogen inhibitors.

    Aliases: arginine/serine-rich antibody, Cdc2 related kinase arginine/serine rich antibody, CDC2 related protein kinase 7 antibody, Cdc2-related kinase antibody, CDC2-related protein kinase 7 antibody, Cdk12 antibody, CDK12_HUMAN antibody, Cell division cycle 2 related protein kinase 7 antibody, Cell division cycle 2-related protein kinase 7 antibody, Cell division protein kinase 12 antibody, CRK7 antibody, CRKR antibody, CrkRS antibody, Cyclin-dependent kinase 12 antibody, EC 2.7.11.22 antibody, hCDK12 antibody, kiaa0904 antibody, Pksc antibody

    UniProt
    Q9NYV4
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