ATF6 抗体 (AA 1-194)
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- 抗原 See all ATF6 抗体
- ATF6 (Activating Transcription Factor 6 (ATF6))
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抗原表位
- AA 1-194
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATF6 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Antigen Affinity purified & Affinity purified
- 免疫原
- Recombinant Human Cyclic AMP-dependent transcription factor ATF-6 alpha protein (1-194AA)
- 亚型
- IgG
- Top Product
- Discover our top product ATF6 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:100-1:500, IF:1:100-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- ATF6 (Activating Transcription Factor 6 (ATF6))
- 别名
- ATF6 (ATF6 产品)
- 别名
- ATF-6-like antibody, GB16435 antibody, ATF6 antibody, Atf6 antibody, ATF6A antibody, 9130025P16Rik antibody, 9630036G24 antibody, AA789574 antibody, Atf6alpha antibody, ESTM49 antibody, activating transcription factor 6 antibody, uncharacterized LOC412432 antibody, activating transcription factor 6 S homeolog antibody, cyclic AMP-dependent transcription factor ATF-6 alpha antibody, ATF6 antibody, LOC412432 antibody, atf6.S antibody, LOC100122162 antibody, Atf6 antibody
- 背景
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Background: Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5\'-CCAC[GA]-3\'half of the ER stress response element (ERSE) (5\'-CCAAT-N(9)-CCAC[GA]-3\') and of ERSE II (5\'-ATTGG-N-CCACG-3\'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
Aliases: Activating transcription factor 6 alpha antibody, Activating transcription factor 6 antibody, ATF 6 antibody, ATF6 alpha antibody, ATF6 antibody, ATF6-alpha antibody, ATF6A antibody, ATF6A_HUMAN antibody, cAMP dependent transcription factor ATF 6 alpha antibody, cAMP-dependent transcription factor ATF-6 alpha antibody, Cyclic AMP dependent transcription factor ATF 6 alpha antibody, DKFZp686P2194 antibody, ESTM49 antibody, FLJ21663 antibody, Processed cyclic AMP dependent transcription factor ATF 6 alpha antibody, Processed cyclic AMP-dependent transcription factor ATF-6 alpha antibody
- UniProt
- P18850
- 途径
- ER-Nucleus Signaling, Unfolded Protein Response
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