CRTC1 抗体 (AA 1-248) (HRP)
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- 抗原 See all CRTC1 抗体
- CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
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抗原表位
- AA 1-248
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRTC1 antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human CREB-regulated transcription coactivator 1 protein (1-248AA)
- 亚型
- IgG
- Top Product
- Discover our top product CRTC1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
- 别名
- CRTC1 (CRTC1 产品)
- 别名
- MECT1 antibody, TORC-1 antibody, TORC1 antibody, WAMTP1 antibody, AI413414 antibody, Mect1 antibody, R74955 antibody, mKIAA0616 antibody, CRTC1 antibody, crtc1 antibody, fc68c05 antibody, pde4cb antibody, si:ch211-255d18.1 antibody, si:ch211-255d18.8 antibody, wu:fc68c05 antibody, CREB regulated transcription coactivator 1 antibody, CREB regulated transcription coactivator 1b antibody, CRTC1 antibody, Crtc1 antibody, crtc1 antibody, crtc1b antibody
- 背景
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Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
Aliases: KIAA0616 antibody, CREB regulated transcription coactivator 1 antibody, CREB-regulated transcription coactivator 1 antibody, CRTC1 antibody, CRTC1_HUMAN antibody, FLJ14027 antibody, MECT 1 antibody, Mucoepidermoid carcinoma translocated 1 antibody, Mucoepidermoid carcinoma translocated protein 1 antibody, TORC-1 antibody, TORC1 antibody, Transducer of CREB protein 1 antibody, Transducer of regulated cAMP response element binding protein 1 antibody, Transducer of regulated cAMP response element-binding protein (CREB) 1 antibody, Transducer of regulated cAMP response element-binding protein 1 antibody, WAMTP1 antibody
- UniProt
- Q6UUV9
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