CBP 抗体 (AA 2217-2442)
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- 抗原 See all CBP (CREBBP) 抗体
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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抗原表位
- AA 2217-2442
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CBP antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human CREB-binding protein (2217-2442AA)
- 亚型
- IgG
- Top Product
- Discover our top product CREBBP Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
- 别名
- CREBBP (CREBBP 产品)
- 别名
- CBP antibody, KAT3A antibody, RSTS antibody, AW558298 antibody, CBP/p300 antibody, p300/CBP antibody, RTS antibody, cbp antibody, crebbp antibody, kat3a antibody, rsts antibody, hmm291030 antibody, Nejire antibody, CREB binding protein antibody, CREB binding protein L homeolog antibody, histone acetyltransferase p300 antibody, CREBBP antibody, Crebbp antibody, crebbp.L antibody, LOC100123220 antibody
- 背景
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Background: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).
Aliases: CBP antibody, CBP_HUMAN antibody, CREB binding protein antibody, CREB-binding protein antibody, Crebbp antibody, Cyclic AMP responsive enhancer binding protein antibody, KAT3A antibody, RSTS antibody, RTS antibody, Rubinstein Taybi syndrome antibody
- UniProt
- Q92793
- 途径
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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