Coxsackie Adenovirus Receptor 抗体 (AA 259-365)
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- 抗原 See all Coxsackie Adenovirus Receptor (CXADR) 抗体
- Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))
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抗原表位
- AA 259-365
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Coxsackie Adenovirus Receptor antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Coxsackievirus and adenovirus receptor protein (259-365AA)
- 亚型
- IgG
- Top Product
- Discover our top product CXADR Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))
- 别名
- CXADR (CXADR 产品)
- 别名
- CAR antibody, CAR4/6 antibody, HCAR antibody, Car1 antibody, car antibody, cb331 antibody, fb76g12 antibody, wu:fb76g12 antibody, 2610206D03Rik antibody, AU016810 antibody, AW553441 antibody, MCAR antibody, MCVADR antibody, hcar antibody, xCAR antibody, CXADR antibody, CXADR, Ig-like cell adhesion molecule antibody, coxsackie virus and adenovirus receptor antibody, CXADR, Ig-like cell adhesion molecule L homeolog antibody, CXADR antibody, Cxadr antibody, cxadr antibody, cxadr.L antibody
- 背景
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Background: Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
Aliases: 46 kD coxsackievirus and adenovirus receptor CAR protein antibody, 46 kD coxsackievirus and adenovirus receptor protein antibody, CAR antibody, CAR4/6 antibody, Coxsackie virus and adenovirus receptor antibody, Coxsackie virus B receptor antibody, Coxsackievirus and adenovirus receptor antibody, Coxsackievirus B adenovirus receptor antibody, Coxsackievirus B-adenovirus receptor antibody, CVB3 binding protein antibody, CVB3-binding protein antibody, Cxadr antibody, CXADR Ig like cell adhesion molecule antibody, CXAR_HUMAN antibody, hCAR antibody, HCVADR antibody
- UniProt
- P78310
- 途径
- Cell-Cell Junction Organization
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