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COPS7B 抗体 (AA 1-157) (FITC)

COPS7B 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7148505
发货至: 中国
  • 抗原 See all COPS7B 抗体
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-157
    适用
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 30
    • 2
    克隆类型
    • 32
    多克隆
    标记
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COPS7B antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human COP9 signalosome complex subunit 7b protein (1-157AA)
    亚型
    IgG
    Top Product
    Discover our top product COPS7B Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    别名
    COPS7B (COPS7B 产品)
    别名
    MGC114836 antibody, D1Wsu66e antibody, E130114M23 antibody, CSN7B antibody, COP9 signalosome subunit 7B antibody, COP9 signalosome subunit 7B S homeolog antibody, Cops7b antibody, COPS7B antibody, cops7b.S antibody
    背景

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    Aliases: COP9 Complex Homolog Subunit 7b antibody, COP9 Constitutive Photomorphogenic Homolog Subunit 7b antibody, COP9 Signalasome Subunit 7b antibody, COP9 signalosome complex subunit 7b antibody, COPS7B antibody, CSN7B_HUMAN antibody, JAB1 Containing Signalosome Subunit 7b antibody, JAB1-containing signalosome subunit 7b antibody, SGN7b antibody, Signalosome subunit 7b antibody

    UniProt
    Q9H9Q2
    途径
    Cell Division Cycle
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