COPS7A 抗体 (AA 1-275)
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- 抗原 See all COPS7A 抗体
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
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抗原表位
- AA 1-275
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COPS7A antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human COP9 signalosome complex subunit 7a protein (1-275AA)
- 亚型
- IgG
- Top Product
- Discover our top product COPS7A Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- COPS7A (COP9 Signalosome Complex Subunit 7a (COPS7A))
- 别名
- COPS7A (COPS7A 产品)
- 别名
- D6Ertd35e antibody, CSN7A antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, Cops7a antibody
- 背景
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Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Aliases: COP9 complex subunit 7a antibody, COP9 constitutive photomorphogenic homolog subunit 7A antibody, COP9 signalosome complex subunit 7a antibody, COP9 signalosome subunit 7A antibody, COPS7A antibody, CSN7A antibody, CSN7A_HUMAN antibody, Dermal papilla derived protein 10 antibody, Dermal papilla-derived protein 10 antibody, DERP10 antibody, JAB1 containing signalosome subunit 7a antibody, JAB1-containing signalosome subunit 7a antibody, SGN7a antibody, Signalosome subunit 7a antibody
- UniProt
- Q9UBW8
- 途径
- Cell Division Cycle
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