GPS1 抗体 (AA 222-491)
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- 抗原 See all GPS1 抗体
- GPS1 (G Protein Pathway Suppressor 1 (GPS1))
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抗原表位
- AA 222-491
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human COP9 signalosome complex subunit 1 protein (222-491AA)
- 亚型
- IgG
- Top Product
- Discover our top product GPS1 Primary Antibody
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- 应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- GPS1 (G Protein Pathway Suppressor 1 (GPS1))
- 别名
- GPS1 (GPS1 产品)
- 别名
- COPS1 antibody, CSN1 antibody, Cops1 antibody, Csn1 antibody, R75577 antibody, Sgn1 antibody, im:6909260 antibody, im:7145572 antibody, zgc:154082 antibody, csn1 antibody, ARABIDOPSIS THALIANA FUSCA 6 antibody, ATFUS6 antibody, ATSK31 antibody, CONSTITUTIVE PHOTOMORPHOGENIC 11 antibody, COP11 antibody, COP9 SIGNALOSOME SUBUNIT 1 antibody, EMB78 antibody, EMBRYO DEFECTIVE 78 antibody, FUSCA 6 antibody, SHAGGY-LIKE KINASE 31 antibody, SK31 antibody, G protein pathway suppressor 1 antibody, casein alpha s1 antibody, G protein pathway suppressor 1 L homeolog antibody, COP9 signalosome complex subunit 1 antibody, GPS1 antibody, CSN1S1 antibody, LOC693104 antibody, CC1G_07518 antibody, Bm1_55055 antibody, Gps1 antibody, gps1 antibody, gps1.L antibody, FUS6 antibody, csn-1 antibody
- 背景
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Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.
Aliases: COP9 signalosome complex subunit 1 antibody, COP9 signalosome subunit 1 antibody, COPS1 antibody, CSN 1 antibody, CSN1_HUMAN antibody, FUS6/COP11, Arabidopsis, homolog of antibody, G protein pathway suppressor 1 antibody, GPS-1 antibody, Gps1 antibody, JAB1-containing signalosome subunit 1 antibody, Protein GPS1 antibody, Protein MFH antibody, SGN1 antibody, Signalosome subunit 1 antibody
- UniProt
- Q13098
- 途径
- Cell Division Cycle
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