COL4a2 抗体 (AA 1493-1712)
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- 抗原 See all COL4a2 (COL4A2) 抗体
- COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
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抗原表位
- AA 1493-1712
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This COL4a2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Collagen alpha-2(IV) chain protein (1493-1712AA)
- 亚型
- IgG
- Top Product
- Discover our top product COL4A2 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))
- 别名
- COL4A2 (COL4A2 产品)
- 别名
- col4a2-a antibody, zCanstatin antibody, ICH antibody, POREN2 antibody, Col4a-2 antibody, collagen, type IV, alpha 2 L homeolog antibody, collagen type IV alpha 2 chain antibody, collagen, type IV, alpha 2 antibody, col4a2.L antibody, COL4A2 antibody, col4a2 antibody, Col4a2 antibody
- 背景
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Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a \\\'chicken-wire\\\' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.
Aliases: Canstatin antibody, CO4A2_HUMAN antibody, COL4A 2 antibody, Col4a2 antibody, Collagen alpha 2(IV) chain antibody, Collagen, type IV, alpha 2 antibody
- UniProt
- P08572
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