CLASP2 抗体 (AA 226-381)
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- 抗原 See all CLASP2 抗体
- CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
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抗原表位
- AA 226-381
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CLASP2 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human CLIP-associating protein 2 protein (226-381AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))
- 别名
- CLASP2 (CLASP2 产品)
- 别名
- zgc:77279 antibody, DKFZp459M112 antibody, 1500004F14Rik antibody, 8030404L10Rik antibody, C77448 antibody, CLASP2beta antibody, mKIAA0627 antibody, cytoplasmic linker associated protein 2 antibody, CLIP associating protein 2 antibody, clasp2 antibody, CLASP2 antibody, Clasp2 antibody
- 背景
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Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Aliases: CLAP2_HUMAN antibody, CLASP 2 antibody, Clasp2 antibody, CLIP associating protein 2 antibody, CLIP-associating protein 2 antibody, Cytoplasmic linker associated protein 2 antibody, Cytoplasmic linker-associated protein 2 antibody, hOrbit2 antibody, KIAA0627 antibody, Multiple asters (Mast) like homolog 2 antibody, Protein Orbit homolog 2 antibody
- UniProt
- O75122
- 途径
- Microtubule Dynamics, Maintenance of Protein Location
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