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NG2 抗体 (AA 1950-2210)

MCSP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7147644
发货至: 中国
  • 抗原 See all NG2 (MCSP) 抗体
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    抗原表位
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1950-2210
    适用
    • 44
    • 23
    • 17
    • 1
    宿主
    • 41
    • 14
    克隆类型
    • 31
    • 23
    • 1
    多克隆
    标记
    • 27
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This NG2 antibody is un-conjugated
    应用范围
    • 29
    • 19
    • 10
    • 10
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Chondroitin sulfate proteoglycan 4 protein (1950-2210AA)
    亚型
    IgG
    Top Product
    Discover our top product MCSP Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    别名
    CSPG4 (MCSP 产品)
    别名
    HMW-MAA antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, MSK16 antibody, NG2 antibody, 4732461B14Rik antibody, AN2 antibody, Ng2 antibody, HSMCSGEN1 antibody, MCS antibody, chondroitin sulfate proteoglycan 4 antibody, sperm mitochondria associated cysteine rich protein antibody, CSPG4 antibody, Cspg4 antibody, SMCP antibody
    背景

    Background: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades.

    Aliases: 4732461B14Rik antibody, AN2 antibody, AN2 proteoglycan antibody, Chondroitin sulfate proteoglycan 4 (melanoma-associated) antibody, Chondroitin sulfate proteoglycan 4 antibody, Chondroitin sulfate proteoglycan NG2 antibody, Cspg4 antibody, Cspg4 chondroitin sulfate proteoglycan 4 antibody, CSPG4_HUMAN antibody, HMW-MAA antibody, HSN tumor-specific antigen antibody, Kiaa4232 antibody, MCSP antibody, MCSPG antibody, MEL-CSPG antibody, Melanoma chondroitin sulfate proteoglycan antibody, Melanoma-associated chondroitin sulfate proteoglycan antibody, MELCSPG antibody, MSK16 antibody, NG2 antibody

    UniProt
    Q6UVK1
    途径
    Glycosaminoglycan Metabolic Process
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