CH25H 抗体 (AA 142-272) (HRP)
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- 抗原 See all CH25H 抗体
- CH25H (Cholesterol 25-Hydroxylase (CH25H))
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抗原表位
- AA 142-272
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CH25H antibody is conjugated to HRP
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Cholesterol 25-hydroxylase protein (142-272AA)
- 亚型
- IgG
- Top Product
- Discover our top product CH25H Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CH25H (Cholesterol 25-Hydroxylase (CH25H))
- 别名
- CH25H (CH25H 产品)
- 别名
- CH25H antibody, zgc:101688 antibody, MGC143045 antibody, C25H antibody, AI462618 antibody, m25OH antibody, cholesterol 25-hydroxylase antibody, cholesterol 25-hydroxylase L homeolog antibody, CH25H antibody, ch25h antibody, Ch25h antibody, ch25h.L antibody
- 背景
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Background: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
Aliases: CH25H antibody, Cholesterol 25-hydroxylase antibody, EC 1.14.99.38 antibody, Cholesterol 25-monooxygenase antibody, h25OH antibody
- UniProt
- O95992
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