CMKLR1 抗体 (AA 321-373)
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- 抗原 See all CMKLR1 抗体
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
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抗原表位
- AA 321-373
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CMKLR1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Chemokine-like receptor 1 protein (321-373AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- 别名
- CMKLR1 (CMKLR1 产品)
- 别名
- CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
- 背景
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Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
Aliases: CHEMERINR antibody, Chemokine like receptor 1 antibody, Chemokine-like receptor 1 antibody, CHEMR23 antibody, CMKLR1 antibody, CML1_HUMAN antibody, DEZ antibody, G protein coupled receptor ChemR23 antibody, G protein coupled receptor DEZ antibody, G-protein coupled receptor ChemR23 antibody, G-protein coupled receptor DEZ antibody, Orphan G protein coupled receptor antibody, Orphan G protein coupled receptor Dez antibody, Resolvin E1 receptor antibody, RVER1 antibody
- UniProt
- Q99788
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