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HUS1 抗体 (AA 2-280)

HUS1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7147541
发货至: 中国
  • 抗原 See all HUS1 抗体
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-280
    适用
    • 51
    • 28
    • 15
    宿主
    • 62
    • 4
    克隆类型
    • 65
    • 1
    多克隆
    标记
    • 23
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HUS1 antibody is un-conjugated
    应用范围
    • 31
    • 26
    • 13
    • 13
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Checkpoint protein HUS1 protein (2-280AA)
    亚型
    IgG
    Top Product
    Discover our top product HUS1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    别名
    HUS1 (HUS1 产品)
    别名
    hHUS1 antibody, mHus1 antibody, XHus1 antibody, hus1 antibody, HUS1 checkpoint clamp component antibody, checkpoint clamp complex protein Hus1 antibody, HUS1 checkpoint clamp component L homeolog antibody, HUS1 antibody, Hus1 antibody, hus1 antibody, hus1.L antibody
    背景

    Background: Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3\\\'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds, endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths, and DNA ligase I (LIG1) on long-patch base excision repair substrates. The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.

    Aliases: Checkpoint protein HUS1 antibody, hHUS1 antibody, HUS1 (S. pombe) checkpoint homolog antibody, Hus1 antibody, HUS1 checkpoint homolog (S. pombe) antibody, HUS1 Checkpoint Protein antibody, HUS1 protein antibody, HUS1+ - like protein antibody, HUS1_HUMAN antibody, Hydroxyurea-sensitive 1, S. pombe, homolog of antibody

    UniProt
    O60921
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