CHMP6 抗体 (AA 2-201) (HRP)
Quick Overview for CHMP6 抗体 (AA 2-201) (HRP) (ABIN7147536)
抗原
See all CHMP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-201
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Charged multivesicular body protein 6 protein (2-201AA)
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亚型
- IgG
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anti-Charged Multivesicular Body Protein 6 (CHMP6) (AA 2-201) antibody
CHMP6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 6 (CHMP6) antibodyCHMP6 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 6 (CHMP6) antibodyCHMP6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))
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别名
- CHMP6
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背景
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Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.
Aliases: Charged multivesicular body protein 6 antibody, chmp6 antibody, CHMP6_HUMAN antibody, Chromatin modifying protein 6 antibody, Chromatin-modifying protein 6 antibody, FLJ11749 antibody, hVps 20 antibody, hVps20 antibody, novel SNF7 protein antibody, OTTMUSP00000004363 antibody, RGD1565325 antibody, RP24 225K18.4 antibody, Vacuolar protein sorting associated protein 20 antibody, Vacuolar protein sorting-associated protein 20 antibody, Vps 20 antibody, Vps20 antibody
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UniProt
- Q96FZ7
抗原
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