MAPKAP Kinase 2 抗体 (pSer272)
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- 抗原 See all MAPKAP Kinase 2 (MAPKAPK2) 抗体
- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
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抗原表位
- pSer272
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适用
- 人, 小鼠, 大鼠, Cow, 小鸡, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAPKAP Kinase 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 大鼠, 小鸡, 猪, 牛
- 纯化方法
- purified by Protein A and peptide affinity chromatography
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human MAPKAPK2 around the phosphorylation site of pSer272
- 亚型
- IgG
- Top Product
- Discover our top product MAPKAPK2 Primary Antibody
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- 应用备注
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WB(1:100-500)
Optimal working dilution should be determined by the investigator. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 µg/µL
- 缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C for 12 months
- 有效期
- 12 months
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- 抗原
- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
- 别名
- MAPKAPK2 (MAPKAPK2 产品)
- 别名
- mapkapk2 antibody, wu:fb30e10 antibody, wu:fc56c10 antibody, wu:fi03a01 antibody, MGC78852 antibody, MAPKAPK2 antibody, AA960234 antibody, MAPKAP-K2 antibody, MK-2 antibody, MK2 antibody, Rps6kc1 antibody, mitogen-activated protein kinase-activated protein kinase 2a antibody, mitogen-activated protein kinase-activated protein kinase 2 L homeolog antibody, mitogen-activated protein kinase-activated protein kinase 2 antibody, MAP kinase-activated protein kinase 2 antibody, mapkapk2a antibody, mapkapk2.L antibody, MAPKAPK2 antibody, Mapkapk2 antibody
- 背景
- MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.
- 分子量
- 44kDa
- 基因ID
- 9261
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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