CHMP2B 抗体 (AA 1-213)
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- 抗原 See all CHMP2B 抗体
- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
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抗原表位
- AA 1-213
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHMP2B antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Charged multivesicular body protein 2b protein (1-213AA)
- 亚型
- IgG
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
- 别名
- CHMP2B (CHMP2B 产品)
- 别名
- ALS17 antibody, CHMP2.5 antibody, DMT1 antibody, VPS2-2 antibody, VPS2B antibody, 1190006E07Rik antibody, RGD1306781 antibody, chmp2b antibody, chmp2bl antibody, zgc:77025 antibody, si:ch211-224m9.5 antibody, CHMP2B antibody, cg4618 antibody, chmp2.5 antibody, dmt1 antibody, vps2-2 antibody, vps2b antibody, CHMP2b-B antibody, chmp2b-a antibody, chmp2b-b antibody, charged multivesicular body protein 2B antibody, charged multivesicular body protein 2Bb antibody, charged multivesicular body protein 2Ba antibody, charged multivesicular body protein 2B pseudogene antibody, charged multivesicular body protein 2B S homeolog antibody, charged multivesicular body protein 2B L homeolog antibody, CHMP2B antibody, Chmp2b antibody, chmp2bb antibody, chmp2ba antibody, LOC747711 antibody, chmp2b.S antibody, chmp2b.L antibody
- 背景
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Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Aliases: ALS17 antibody, Charged multivesicular body protein 2b antibody, CHM2B_HUMAN antibody, CHMP family, member 2B antibody, CHMP2.5 antibody, CHMP2b antibody, Chromatin modifying protein 2b antibody, Chromatin-modifying protein 2b antibody, DMT1 antibody, hVps2-2 antibody, Vacuolar protein sorting 2, yeast, homolog of, B antibody, Vacuolar protein sorting 2-2 antibody, Vacuolar protein sorting-associated protein 2-2 antibody, VPS2 homolog B antibody, Vps2-2 antibody, VPS2B antibody
- UniProt
- Q9UQN3
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