CHMP1A 抗体 (AA 1-196)
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- 抗原 See all CHMP1A 抗体
- CHMP1A (Charged Multivesicular Body Protein 1A (CHMP1A))
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抗原表位
- AA 1-196
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHMP1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Charged multivesicular body protein 1a protein (1-196AA)
- 亚型
- IgG
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anti-Charged Multivesicular Body Protein 1A (CHMP1A) antibody
CHMP1A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) (AA 1-196) antibodyCHMP1A 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) (AA 51-150) antibodyCHMP1A 适用: 人, 小鼠 IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) antibodyCHMP1A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 1A (CHMP1A) (AA 1-196) antibodyCHMP1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CHMP1A (Charged Multivesicular Body Protein 1A (CHMP1A))
- 别名
- CHMP1A (CHMP1A 产品)
- 别名
- CHMP1 antibody, PCH8 antibody, PCOLN3 antibody, PRSM1 antibody, VPS46-1 antibody, VPS46A antibody, 2900018H07Rik antibody, Pcoln3 antibody, charged multivesicular body protein 1A antibody, CHMP1A antibody, Chmp1a antibody
- 背景
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Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.
Aliases: Charged multivesicular body protein 1a antibody, CHM1A_HUMAN antibody, CHMP1a antibody, Chromatin modifying protein 1a antibody, Chromatin-modifying protein 1a antibody, hVps46 1 antibody, hVps46-1 antibody, KIAA0047 antibody, Metalloprotease 1 antibody, PCOLN3 antibody, Procollagen (type III) N endopeptidase antibody, PRSM1 antibody, Vacuolar protein sorting 46 1 antibody, Vacuolar protein sorting-associated protein 46-1 antibody, Vps46 1 antibody, Vps46-1 antibody
- UniProt
- Q9HD42
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