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MCAM 抗体 (AA 50-646)

MCAM 适用: 人 FACS, WB, IF, ELISA 宿主: 小鼠 Monoclonal 4D10C7 unconjugated
产品编号 ABIN7147325
发货至: 中国
  • 抗原 See all MCAM 抗体
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    抗原表位
    • 16
    • 13
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    • 5
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    AA 50-646
    适用
    • 123
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    宿主
    • 95
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    小鼠
    克隆类型
    • 88
    • 62
    单克隆
    标记
    • 69
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    This MCAM antibody is un-conjugated
    应用范围
    • 83
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    Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), ELISA
    交叉反应
    纯化方法
    Protein G purified
    免疫原
    Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)
    克隆位点
    4D10C7
    亚型
    IgG2a
    Top Product
    Discover our top product MCAM Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    别名
    CD146 (MCAM 产品)
    别名
    CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
    背景

    Background: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

    Aliases: Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146), MCAM, MUC18

    UniProt
    P43121
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