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CADM1 抗体 (AA 45-344)

CADM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7147246
发货至: 中国
  • 抗原 See all CADM1 抗体
    CADM1 (Cell Adhesion Molecule 1 (CADM1))
    抗原表位
    • 16
    • 10
    • 10
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 45-344
    适用
    • 60
    • 44
    • 27
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 58
    • 3
    • 2
    克隆类型
    • 61
    • 2
    多克隆
    标记
    • 29
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This CADM1 antibody is un-conjugated
    应用范围
    • 57
    • 26
    • 17
    • 17
    • 14
    • 14
    • 9
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Cell adhesion molecule 1 protein (45-344AA)
    亚型
    IgG
    Top Product
    Discover our top product CADM1 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CADM1 (Cell Adhesion Molecule 1 (CADM1))
    别名
    CADM1 (CADM1 产品)
    别名
    BL2 antibody, IGSF4 antibody, IGSF4A antibody, NECL2 antibody, Necl-2 antibody, RA175 antibody, ST17 antibody, SYNCAM antibody, TSLC1 antibody, sTSLC-1 antibody, sgIGSF antibody, synCAM1 antibody, bl2 antibody, igsf4 antibody, igsf4a antibody, necl-2 antibody, necl2 antibody, ra175 antibody, sgigsf antibody, st17 antibody, stslc-1 antibody, syncam antibody, syncam1 antibody, tslc1 antibody, xnecl2 antibody, 2900073G06Rik antibody, 3100001I08Rik antibody, AI987920 antibody, Bl2 antibody, Igsf4 antibody, Igsf4a antibody, Necl2 antibody, RA175A antibody, RA175B antibody, RA175C antibody, RA175N antibody, SgIGSF antibody, SynCam antibody, Tslc1 antibody, SynCAM1 antibody, cell adhesion molecule 1 antibody, cell adhesion molecule 1 L homeolog antibody, CADM1 antibody, cadm1.L antibody, Cadm1 antibody
    背景

    Background: Mediates homophilic cell-cell adhesion in a Ca2+-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca2+-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly (By similarity). May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.

    Aliases: BL2 antibody, Cadm1 antibody, CADM1_HUMAN antibody, Cell adhesion molecule 1 antibody, DKFZp686F1789 antibody, IgSF4 antibody, IGSF4A antibody, Immunoglobulin superfamily member 4 antibody, MGC149785 antibody, MGC51880 antibody, NECL-2 antibody, NECL2 antibody, Nectin like 2 antibody, Nectin-like protein 2 antibody, RA175 antibody, SgIGSF antibody, Spermatogenic immunoglobulin superfamily antibody, ST17 antibody, sTSLC 1 antibody, Synaptic cell adhesion molecule antibody, SynCAM antibody, SynCAM1 antibody, TSLC-1 antibody, TSLC1 antibody, Tumor suppressor in lung cancer 1 antibody

    UniProt
    Q9BY67
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
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