CNOT3 抗体 (AA 257-395)
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- 抗原 See all CNOT3 抗体
- CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
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抗原表位
- AA 257-395
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CNOT3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human CCR4-NOT transcription complex subunit 3 protein (257-395AA)
- 亚型
- IgG
- Top Product
- Discover our top product CNOT3 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))
- 别名
- CNOT3 (CNOT3 产品)
- 背景
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Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem (ES) cell identity.
Aliases: CCR4 associated factor 3 antibody, CCR4-associated factor 3 antibody, CCR4-NOT transcription complex subunit 3 antibody, CNOT3 antibody, CNOT3_HUMAN antibody, KIAA0691 antibody, LENG2 antibody, Leukocyte receptor cluster member 2 antibody, negative regulator of transcription 3, S. cerevisiae, homolog of antibody, NOT3 (negative regulator of transcription 3, yeast) homolog antibody, NOT3 antibody, NOT3H antibody
- UniProt
- O75175
- 途径
- Stem Cell Maintenance
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