CATSPER4 抗体 (AA 306-472) (Biotin)
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- 抗原 See all CATSPER4 抗体
- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
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抗原表位
- AA 306-472
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CATSPER4 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)
- 亚型
- IgG
- Top Product
- Discover our top product CATSPER4 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
- 别名
- CATSPER4 (CATSPER4 产品)
- 别名
- RGD1565213 antibody, 4933412L05 antibody, cation channel, sperm associated 4 antibody, cation channel sperm associated 4 antibody, Catsper4 antibody, CATSPER4 antibody
- 背景
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Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .
Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody
- UniProt
- Q7RTX7
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