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CATSPER2 抗体 (AA 5-112)

CATSPER2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7147031
发货至: 中国
  • 抗原 See all CATSPER2 抗体
    CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))
    抗原表位
    • 14
    • 10
    • 5
    • 3
    • 1
    AA 5-112
    适用
    • 27
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 27
    克隆类型
    • 27
    多克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    This CATSPER2 antibody is un-conjugated
    应用范围
    • 23
    • 17
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Cation channel sperm-associated protein 2 protein (5-112AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CATSPER2 (Cation Channel, Sperm Associated 2 (CATSPER2))
    别名
    CATSPER2 (CATSPER2 产品)
    别名
    CATSPER2 antibody, cation channel, sperm associated 2 antibody, cation channel sperm associated 2 antibody, CATSPER2 antibody, Catsper2 antibody
    背景

    Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .

    Aliases: CATSPER2 antibody, Cation channel sperm-associated protein 2 antibody, CatSper2 antibody

    UniProt
    Q96P56
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