CARD16 抗体 (AA 1-197) (Biotin)
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- 抗原 See all CARD16 抗体
- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
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抗原表位
- AA 1-197
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CARD16 antibody is conjugated to Biotin
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应用范围
- ELISA
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human Caspase recruitment domain-containing protein 16 protein (1-197AA)
- 亚型
- IgG
- Top Product
- Discover our top product CARD16 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CARD16 (Caspase Recruitment Domain Family, Member 16 (CARD16))
- 别名
- CARD16 (CARD16 产品)
- 别名
- COP antibody, COP1 antibody, PSEUDO-ICE antibody, caspase recruitment domain family member 16 antibody, CARD16 antibody
- 背景
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Background: Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Aliases: CAR16_HUMAN antibody, CARD only domain-containing protein 1 antibody, CARD only protein antibody, CARD16 antibody, Caspase recruitment domain family, member 16 antibody, Caspase recruitment domain-containing protein 16 antibody, Caspase-1 dominant-negative inhibitor pseudo-ICE antibody, Caspase-1 inhibitor COP antibody, COP antibody, COP1 antibody, Pseudo interleukin 1 beta converting enzyme antibody, Pseudo interleukin-1 beta converting enzyme antibody, Pseudo interleukin-1beta converting enzyme antibody, PSEUDO-ICE antibody
- UniProt
- Q5EG05
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