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SS18L1 抗体 (AA 47-396)

SS18L1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7146400
发货至: 中国
  • 抗原 See all SS18L1 抗体
    SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 47-396
    适用
    • 27
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 26
    • 1
    克隆类型
    • 26
    • 1
    多克隆
    标记
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    This SS18L1 antibody is un-conjugated
    应用范围
    • 22
    • 18
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Calcium-responsive transactivator protein (47-396AA)
    亚型
    IgG
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
    别名
    SS18L1 (SS18L1 产品)
    别名
    crest antibody, CREST antibody, LP2261 antibody, A230053O16Rik antibody, SS18L1, nBAF chromatin remodeling complex subunit antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, synovial sarcoma translocation gene on chromosome 18-like 1 S homeolog antibody, SS18, nBAF chromatin remodeling complex subunit like 1 antibody, SS18L1 antibody, ss18l1 antibody, ss18l1.S antibody, Ss18l1 antibody
    背景

    Background: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).

    Aliases: Calcium-responsive transactivator antibody, CREST antibody, CREST_HUMAN antibody, KIAA0693 antibody, LP2261 antibody, MGC26711 antibody, MGC78386 antibody, sarcoma translocation gene on chromosome18like1 antibody, SS18 antibody, SS18-like protein 1 antibody, SS18L1 antibody, SS18L1 nBAF chromatin remodeling complex antibody, SSXT antibody, synovial sarcoma translocation antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, SYT homolog 1 antibody

    UniProt
    O75177
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